The Challenge
Generating reliable evidence to support the health and wellbeing of mothers during their pregnancy journeys continues to be a challenge for the pharmaceutical industry.
Maternal mortality rates in the U.S. increased by 40% in 2021.
According to the FDA, “pregnancy registry data is not sufficient to assess the safety of products during pregnancy. Other methods are needed to corroborate registry findings.”
At the onset of COVID-19, there was minimal data and uncertain guidance on whether expectant mothers should be vaccinated.
Our Approach
MOM offers a groundbreaking approach for generating novel insights on the impact of healthcare interventions for pregnant women and their babies. By synchronizing de-identified healthcare records of over 2 million pregnant women with their newborns, clinical researchers can now study a more comprehensive patient journey from pre-pregnancy to birth and beyond.
HealthVerity ID
HVIDs (unique patient identifiers) enable synchronization across data sources (e.g., labs, pharmacy claims, medical claims) and across time, resulting in a patient-centered, longitudinal care journey.
Patient: Mom
Medical Claims
Pregnancy Detected
Diagnosis codes are used for the initial flag of a pregnancy event.
Patient: Mom
Labs
Labs may include routine testing ordered by primary care or specialty providers (e.g., lipid or metabolic panels, urinalysis, blood type, complete blood count), in addition to those associated with prenatal care during a pregnancy episode.
Patient: Mom
Pharmacy
7 in 10 pregnant women take prescription medication during pregnancy and drug exposure during pregnancy can impact maternal or infant outcomes.
Patient: Mom
Medical Claims
The perinatal care journey includes monitoring of complications and comorbidities, provider visits, lab testing, and diagnostic imaging throughout the pregnancy.
Patient: Mom
Hospital
Birth Event
Birth event is used as the index date for date shifting and HIPAA compliance.
Patient: Mom + Baby
HealthVerity ID
An HVID enables synchronization and interoperability across data sources over time, resulting in a patient-centric, longitudinal patient journey.
Patient: Baby
Pharmacy
Prescriptions that had been on hold during pregnancy may now be resumed. New prescriptions for acute or chronic conditions may be identified.
Patient: Mom
Medical Claims
Baby medical visits are captured (e.g., well-child visit), as well as complications or birth defects.
Patient: Baby
EMR
Postpartum follow-up visits are captured, which may include postpartum depression or lactation consulting.
Patient: Mom
Lab
Labs may include newborn screening for genetic disorders or allergy testing.
Patient: Baby
The Data
MOM is sourced from over 150 U.S. healthcare payers, including both commercial and Medicaid payers. Currently comprised of medical claims, pharmacy claims, enrollment data and lab results from the nation’s largest real-world data ecosystem, MOM enables access to more than five years of retrospective data, as well as prospective data options leveraging HealthVerity’s persistent identity resolution technology. EMR and hospital chargemaster data will be added in the months ahead. Data transformations ensure HIPAA compliance while preserving critical data elements, including:
Race and ethnicity
Maternal age buckets
Year of birth
Pregnancy outcomes
Better Outcomes
With access to richer datasets, MOM makes it easy to discover pathways for improved health outcomes.
- Gain a better understanding of outcomes via larger populations (over 2 million mom/baby synchronizations) and more racially diverse populations.
- Access rich data insights without exposing patient identity. MOM de-identifies and date shifts patient data so researchers can explore events that impact health outcomes while keeping patient anonymity.
- Complete post-marketing requirements and improve the development lifecycle. MOM helps refine how to select an ideal patient population for study, what types of analyses can add value to clinical trials and how to properly position efforts around drug labeling.